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Indeed, many researchers agree that e-cigarettes will turn out to be much safer than conventional cigarettes, an idea that e-cigarette companies have made much of in their advertising

Prioritizing the direct and mediating factors of substance use would be beneficial to develop targeted strategies to support successful substance use cessation

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Subgroups analysis Given that the primary hypothesis of this study was null, subgroup analyses were conducted considering drugs received, polymorphism types, and treatment outcomes